Ok, all I'm trying to do is simply set my resolution to 1080p in NWN2 and all it does is crash the damn game.

********* Edit:
Ok I fixed it by going windowed, but I'm disappointed this seems like an easy fix that should have been patched in long ago. Get on the ball GOG this game has been out for quite some time and this is still an issue? Shame...

Same problem, and a surprise, because I could sworn it was fine couple of years ago - when I was playing it for the last time.

You only have to press Alt and Enter to change into windowed mode, make the change, and then Alt and Enter back to fullscreen.
It will be right after that.

It doesn't work for me, I tried everything, even the nwn2.ini but nothing changes

Changing to windowed and back worked for me, thank you.